In a study titled “Hyperbaric oxygen therapy for Bell’s Palsy” (http://www.ncbi.nlm.nih.gov/pubmed/22336830?dopt=Abstract), the authors claim that “Very low quality evidence from one trial suggest that hyperbaric oxygen therapy may be an effective treatment for moderate to server Bell’s palsy”.
In the study they reference two groups: One group of 42 people that received hyperbaric oxygen therapy (2.8 atmospheres for 60 minutes twice daily, five days per week; maximum of 30 ‘dives’) and placebo tablets. A second group of 37 people received “placebo hyperbaric oxygen therapy” and prednisone (40 mg twice daily, reducing over eight days).
My question is, What are we studying? Why were the patients receiving prednisone or a placebo tablet in addition to hyperbaric or “placebo hyperbaric”. Were they trying to evaluate the effects of hyperbaric oxygen therapy or to compare it to the effects of prednisone therapy?
The authors go on to sate that “Facial function recovered in more participants treated with hyperbaric oxygen therapy than with prednisone”. In fact, the numbers are 40 out of 42 patients improved with hyperbaric oxygen therapy and placebo prednisone (a 95% success rate) while 28 out of 37 patients improved with placebo hyperbaric oxygen therapy and 40 mg twice daily of prednisone. I wonder what the numbers would have been if they would have excluded prednisone all together and just done hyperbaric oxygen therapy vs. placebo hyperbaric oxygen therapy?
Fact is, 95% of the patients improved with hyperbaric oxygen therapy and a placebo pill. If I were a physician and I were treating a patient with Bell’s Palsy, I would think that this study would be STRONG evidence to treat patients with 2.8 ata hyperbaric oxygen therapy and a placebo pill. But alas, I am not a physician… as my critics so often point out. My response to them, I am also not the President nor am I of the Cloth; yet I have just as much right to discuss religion and politics as I do medicine.
Closing Thoughts
The authors also report, “There were no reported major complications and all participants completed the trial”. Based on this statement, one might believe that such a therapy may indeed not only be effective but also potentially free of risks. But then again, I may just be a glass is half full kinda guy!
Greg Harris - Hyperbaric Warrior